What does “CB1 receptor” mean?

The cannabinoid receptor found in high density in the brain and central nervous system.

CB1 receptor in plain English

The cannabinoid receptor found in high density in the brain and central nervous system.

CB1 receptors are concentrated in regions handling memory, movement, appetite and pain processing. THC's action here explains both its therapeutic and its intoxicating effects.

They are sparse in the brainstem regions controlling breathing, which is the accepted explanation for why cannabinoid overdose does not cause the respiratory depression that makes opioid overdose lethal.

Frequently asked questions

What does cb1 receptor mean?

The cannabinoid receptor found in high density in the brain and central nervous system.

Sources and further reading

Every factual statement on this page is drawn from the following public sources. Links open in a new tab and are not affiliated with Flora House.

  1. NICE guideline NG144: Cannabis-based medicinal products
  2. NHS: Medical cannabis (and cannabis oils)
  3. MHRA: The supply, manufacture, importation and distribution of unlicensed cannabis-based products for medicinal use

Patient guide · Written by the Flora House editorial team · Last reviewed: 8 September 2026